Comprehensive design of CRISPR gRNAs for nucleases and base editors
On-Target and Off-Target Scoring Algorithms for CRISPR gRNAs
A software tool for personalized and allele-specific CRISPR editing.
CRISPR/Cas-directed HDR genome editing suite: finds+scores gRNA targets, generates donor DNAs, & produces optimal cPCR primer designs.
A flexible and fast sgRNA counter from FASTQ Files
Visualization of CRISPR guide RNAs (gRNAs)
Useful human and mouse data for the crisprVerse ecosystem
Bowtie-based alignment of CRISPR gRNA spacer sequences
Pre-trained models for the crisprScore package
BWA-based alignment of CRISPR gRNA spacer sequences
sg5 sgRNA Designer is a command-line tool for designing CRISPR sgRNAs targeting Drosophila melanogaster genes using the SpCas9/NGG system. Fetches gene sequences directly from the Ensembl REST API, scans both strands for NGG PAM sites, scores each candidate guide, and outputs a ranked list.
UNDER CONSTRUCTION: CRISPR sgRNA quantification pipeline
Script used to cdesign sgRNA sequences based on desired input parameters comparing different web-based tools
predicting sgRNA mismatch activity using keras
SPAN: Profiling of Noncanonical Subgenomic RNAs in SARS-CoV-2 Variants.
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